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IMPORTANT SAFETY INFORMATION AND INDICATIONS

LIPITOR® (atorvastatin calcium) tablets are not for everyone, including anyone who has previously had an allergic reaction to LIPITOR. It is not for those with liver problems. And it is not for women who are nursing, pregnant, or may become pregnant. If you get pregnant, stop taking LIPITOR and call your doctor right away.

If you take LIPITOR® (atorvastatin calcium) tablets, tell your doctor if you feel any new muscle pain or weakness. This could be a sign of rare but serious muscle problems that can lead to kidney problems, including kidney failure.

Tell your doctor about all your medical conditions and all medications you take. This may help avoid serious drug interactions. Your doctor should do blood tests to check your liver function before starting LIPITOR and during your treatment if you have symptoms of liver problems. Call your doctor right away if you have the following symptoms of liver problems - feel tired or weak or have a loss of appetite, upper belly pain, dark amber colored urine or yellowing of your skin or the whites of your eyes.

Tell your doctor if you have diabetes. Elevated blood sugar levels have been reported with statins, including LIPITOR.

Common side effects are diarrhea, upset stomach, muscle and joint pain, and changes in some blood tests.

Talk to your healthcare provider if you have side effects that bother you or that will not go away.

INDICATIONS

LIPITOR is a prescription medicine that lowers cholesterol in the blood. It lowers the LDL-C ("bad” cholesterol) and triglycerides in your blood. It can raise your HDL-C ("good" cholesterol) as well. LIPITOR is for adults and children over 10 whose cholesterol does not come down enough with exercise and a low-fat diet alone.

LIPITOR can lower the risk for heart attack, stroke, certain types of heart surgery, and chest pain in patients who have heart disease or risk factors for heart disease such as age, smoking, high blood pressure, low HDL-C, or heart disease in the family. LIPITOR can lower the risk for heart attack or stroke in patients with diabetes and risk factors such as eye problems, kidney problems, smoking, or high blood pressure.

Limitations of Use: LIPITOR has not been studied in people who have an increase of chylomicrons (Fredrickson Types I and V).

Please see Full Prescribing Information and Patient Information.

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